Hill Equation Calculator

Published August 19, 2026

Calculate pharmacological response using the Hill equation.

Hill Equation

E = E_max × Cⁿ / (EC₅₀ⁿ + Cⁿ)

Concentration (C)

Drug/ligand concentration.

Maximum Effect (Emax)

Maximum possible response.

EC50

Concentration producing 50% of Emax.

Hill Coefficient (n)

Describes the slope/cooperativity of the response.

Response (E)

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% of Emax

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Hill Coefficient

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When the concentration equals EC50, the predicted response is approximately 50% of Emax.